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Last Edited: 11/23/2010

Cohort Study of Girls Nutrition, Environment and Tanner stage
10/2010 - 12/2014


This project is a renewal of the prior 7-year longitudinal study of factors that affect age at pubertal development in girls and is part of the  Breast Cancer & the Environment Research Program (BCERP),. There are several BCERP sites nationwide, suported by the National Institute of Environmental Health Sciences and the National Cancer Institute. This epidemiological study focuses on examining determinants of puberty in girls, measured by breast and pubic hair development, menarche, and growth as potential contributors to breast cancer risk. The determinants being examined include developmental and lifestyle factors, environmental exposures, and genetic polymorphisms. The project is centered at Kaiser Permanente's Division of Research, with co-investigators from several institutes. The design is a longitudinal cohort, with girls recruited from among Kaiser members at ages 6-7 and followed annually since 2004-2005 with questionnaires, physical examinations and biological samples. As a co-investigator, Dr. Windham of CDPH works on all aspects of the study, focusing on environmental exposures and their measurement by biomarkers, as well as on reproductive and hormonal factors.